What are you doing for your local economy? A few years ago, a gentleman scientist was busted at Eli Lilly for making enantiomerically pure methamphetamine and selling it to drug dealers around Indianapolis. Police became suspicious when it was discovered that the meth was of unusually high quality. Business as usual for Big Pharma. Said gentleman scientist was fired and prosecuted. Tough love, I guess. Recently a graduate student from some University of California School (Merced or something) was busted for attempting to make methamphetamine. In principle, he could have synthesized 9 kilos but, for some reason, no traces of methamphetamine were found. This could lead some to speculate that he was a shitty chemist and obviously not ready for a job at big pharma. Or you shouldn’t go to Merced for your graduate education…
I’m rather rabidly anti-meth, which is a significant outlier in my usually consistent social libertarian view of most drugs. Meth, crack and heroin, on the other hand, are my nemesis and all of them have sultry stories not totally invented by the DEA to scare children. I almost feel compelled to qualify my position on that, but I do not see it as very necessary for the same reason I do not need to qualify my position on “stabbing yourself in the penis with a pencil is a sign of mental disease.” Somethings are too obvious.
Which brings me to today’s news. The Dow dropped below 10,000 for the first time since 2002. Whoa. Yet there are very few jumpers these days? It’s easy to jump when you have your golden parachute. Which makes taking a part of the 700 billion unpossibly difficult for CEOs. This has forced the hand of some states to venture into other highly liquid capital markets. Good on Michigan, I say. Marijuana trade keeps cash flowing and growing it within the state means less of it goes to those damn Canadian pot heads and stays within the Wolverine state.
Here is a random picture of a meth user:

I’m sorry for the effusiveness of my position on Meth. I’m maybe a little less sorry this post seems like it was written on it. But, to leave you TOTALLY guessing, here’s a random fucking POP QUIZ, BITCH!
For most 2D NMR experiments you want the sample spinning to be turned off.
- Uhhh... duh. True. (57%, 214 Votes)
- No. Turn the spinning off. (43%, 162 Votes)
Total Voters: 376



I have to confess to the opposite opinion. It seems like we are spending billions around the globe to try to stop our populace from self-medicating with a variety of illegal drugs. Can’t we enlist some chemical ingenuity to synthesize the stuff right here (okay, even in Michigan). If you don’t want Afghanis from growing opium poppies, cut the price.
Not being a user, I don’t know how effective our attempts to prevent its sales actually are. My sense is that we are able to achieve making selling it a career gamble open mainly to lower classes. As a result, those caught and incarcerated are from that group. Luckily, the rich never do drugs and therefore stay out of jail.
It is probably ironic that depression is more widely recognized as afflicting a sizable portion of the population and thus we may be able to prozac our way out of heroin, crack, meth, and others.
Altering your state of mind by using psychoactive drugs has and will always continue to be a part of human nature, we will never get rid of the desire to alter how we perceive the world.
Drug addiction is in no way limited by class, drug of choice may be. Socially acceptable drug abuse involve substances such as alcohol, nicotine, caffeine, opiate pain killers(ex. codeine, or T3’s), and a host of other prescribed medications. We can therefore see a clear distinction between what the “rich” decide should be illegal and what should be legal.
Drug production and sales are in fact the governments way of funding criminal activity. Drugs are illegal, therefore the price will go up…this allows criminal organizations to supply the demand, turning a large (and tax free) profit. We then proceed to pump money into the war against drugs, this does make the drug trade a risky business. While making drug dealing risky it also drives up the price even more, but the fact is that the drug user has decided to take this drug and will continue. Within this rotating circle the drug enforcement agencies only function is to decrease the supply, but the demand will stay up.
What I do hope will happen is governments around the world will begin to realize that it is incredibly cost effective to stop the “war” on drugs and accept them as a blemish on society. Most drug laws are unjust, they cause more harm than good.
Ok, Michael. I just read your comment and I have to say that the DEA’s function is not to decrease supply, but to catch the suppliers, thus bringing in the money from the sale of drugs to the government. When drug dealers pay fines, court costs and probation it only fattens the pockets of the ones on the other side. At least that’s the way I see it. I think you may be trying to make the same point (or similar) and if so, you are right. If all the drug dealers were gone, who would they catch? The process has to continue and that is why street drugs will never be legal.
HA! Are you kidding me? The rich never do drugs therefore stay out of jail!?! NO NO NO – You are VERY mistaken my friend. The rich stay out of jail because they have MONEY! Money is a get out of jail free card. Money can buy anything you want these days. The rich stay out of jail because they can afford to pay their way out! I am a former meth addict and I wish that it wasn’t such an epidemic in our country, but the truth is that it will never go away. Are you blind? I used to be a house keeper for extremely RICH people. I will not name any names, but I do know for a fact that drugs are not confined to one social group. Oh, and yes, the drug companies sell it too. It’s called Desoxyn. I sincerely hope you haven’t written this with a college degree. If so, I feel sorry for anyone who attended the same college as you have. I totally support anyone who wants to express his or her opinion, but please do it with a valid point.
That pop quiz is totally a trick question- do you turn the spinning off, or do you turn the spinning off?
I’m on to your games…
curses.
You’re screwed if you do Solid State NMR.
I don’t get it. 2D SS-NMR is done both with or without spinning. Sometimes both to get different information.
Yeah Rob, I caught on to that too. Trick question all the way, but was that the point or was the asker just dumb?
People aren’t jumping because the windows don’t open in modern buildings.
‘Cause it wasn’t as common as you think:
Between Black Thursday and the end of 1929, only four of the 100 suicides and suicide attempts reported in the New York Times were plunges linked to the crash, and only two took place on Wall Street.
link
Yeah, that makes sense when you sit down and think about it. People were losing their life savings, but EVERYONE was losing their life savings (this was back before FDIC, remember?) Why throw yourself out a window? Debt? Fuck it, it’s the depression, you’re not paying.
Unless there’s something I’m missing here?
Fuck the FDIC. I want to start a bank with open bookkeeping; We’ll proudly display a sign “NOT a member of FDIC”, and anyone can look at our books (clients anonymized, of course) and decide for themselves if they want to keep their money with us.
Having your savings insured just encourages you to be more likely to be reckless with the money.
by which I mean “… just encourages the money holder to be reckless with your money”
Okay, that makes a little more sense. As it stands I’m quite reckless with my money, but that’s no one’s business.
Girl pic: the meth gave, and the meth hath taken away. People can actually take meth for several years and appear fairly normal before their “sudden” rapid decline. Heroin is lot faster – you start falling apart and turn into disfunctional zombie within the first year of use – you are unable hold on job, etc. Meth is much more workplace-friendly, it can even make you look hard-working and energetic for awhile.
What was unusual about the Eli Lilly meth was not the high ee but its high chemical purity – any meth made from optically pure ephedrine or pseudoephedrine will be a pure enantiomer… Both pseudoE and E are unavailable OTC nowadays, so meth making will become more difficult for garage chemists. Professionally-run labs in Mexico won’t be affected though.
you can do opiates and remain functional for years. as long as you have enough of the opiate. the problem is they are so expensive, combined with tolerance that grows very quickly, that you need to keep upping the dose. and then when you dont have enough is when everything starts falling apart…
Dude! The post-meth chick is UBER HOT!
People have psychoactive drugs for ages, so what we ought to concentrate on is making good ones that give you a buzz & then turn into vitamins or something else good. I thought about making a drug called switch that would be like acid, but would have a neutralizing antidote when it’s time to go to work. I guess big pharma is attempting, but too expensive for average joe to buy recreationally.
something that can be expressed in plants
This is a perfect time for long-term investors to put money into the stock market. I’ve never seen it this low in several years, I’m buying another $1500 worth of stock at the end of this month.
One of the NYT’s columnists made that point yesterday, and a commenter replied that at some point the baby boomers will have to liquidate their holdings for retirement. Though it is possible that they might delay retirement because they don’t have enough money it would be out of character – more likely, they will need to draw down their remaining stock more rapidly. In that case, since there are unlikely to be as many purchasers of stock as buyers (because there are so many boomers) and somewhere taxes are going to have go up to pay SS, stocks are likely to decrease substantially until the main wave of retirees is past and the strain on SS (and its deficit-bound “reserves”) is lessened. I don’t have enough faith in this logic to cash out of stocks to bonds, but it does concern me.
I’m sorry I didn’t get back to you – by the time I got to my gmail it seemed too late to reply.
Never too late.
I didn’t incorporate baby boomers into my model, but if I’m looking 40 years down the road…
Sounds like SOMEONE forgot to turn off the spinning when running a 2D last night…
Does meth really make your hair turn blonde? It must be a hit with many then.
Actually, not turning off the spinner when running 2-D NMR does the same thing.
Uhhh, no. I think you mean, NOT turning off the spinner when running 2-D NMR.
Unusually high quality? The website claims that it was a hundred percent pure … I’m guessing that they rounded up.
I’m guessing that his plan was to make a couple hundred grand or a million in a couple of weeks and then get himself laid off … that way , at least financially , would be decades ahead of his time.
Recreational pharma is a clade of monopolies shared between gang corporate and police. To Serve and Protect. A private entrepreneur will not survive breaking into the market any more than a terbinafine pusher could cure athlete’s foot or vaginal candidiasis for a decade – the FDA wanted its fat cut from the Aussies.
Synthesize Armodafinil/Nuvigil for campus consumption. Sulfide to sulfoxide is a nice chiral synthesis. The rare idiosyncratic side effect is lethal shredding of the skin from the inside out. Publication!
Am I the only one that read this and immediately thought:
Okay, I guess images are a no-no. This is was what was supposed to follow the colon.
Vkladani obrazku nefunguje, Kyle. Ten povedeny odkaz je zde:
http://nd.blog.cz/b/bmbclt.blo.....051421.jpg
your czhechoslovakian words have nothing on me.
I was posting couple of things there on Czech forums and I forgot to switch back – I have not even noticed, sorry.
Adding images in your comment section does not work. Please delete my failed attempts at posting a pic above.
Posting images works fine. You posted that “jump fuckers” image correctly the first time you did it. What image isn’t posting?
The image shows in Firefox but not in IE. In IE there is only a blank space.
Oh. Well. People who use IE don’t deserve to see the images anyway.
IAWTC
I think you’re just trying to show off your knowledge of Czech!
great picture.
I’m not a big fan of drugs, but I don’t know if meth is the best example for anything. I would prefer they be legal unless they lead to significant likelihoods of hurting others – PCP, for example seems like a bad idea. I don’t know how bad meth is to others – whether one on it is more likely to commit violence. Making it illegal doesn’t really help – people are likely to commit violence to get it when it’s illegal (to people other than themselves). It becomes a question of how bad the societal damage is from legalizing it versus the damage from people doing it illegally (and what they are likely to do when its illegal, and where the money goes when its not legal).
I liked the quote about the previous drug convict in the C+EN – making a variety of synthetic drugs and leaving them in your lab bench doesn’t seem like the smartest idea.
Note what our friends at Pfizer are doing on their way out. Slash and burn, destroy the community, F-U!!!
Pfizer must be one of the most evil corporations on earth.
http://tinyurl.com/4wdgem
Michiganistan is one of the most awful states in the Universe. This has absolutely nothing to do with their football, mind you, since I’m speaking strictly about their economy. I mean – every time Michigan gets in the news it’s because of economic Fail after Fail after Fail.
Yes, Pfizer is evil. I’m done apologizing for Big Pharma. The “life saving” drugs they’ve been pumping out have done less for saving lives then prolonging the miserable ones. I’m now a cheerleader for Little Pharma. Big pharma can fuck themselves and it seems as though they’re doing just that.
Democratic, Republican, Partisan, Liberal, or whatever you want to call North American political structure is really up to you and however you want to interpret it or understand it.
Either way each person’s perception of this world and society does not change the facts that are going to be outlined.
Reality:
Political structure exists for one purpose only – Economics.
North American Economy dictates world Economy.
The strongest Economic force becomes the dominant political branch.
Example:
War on Drugs: Consumes 80%of overall tax dollars, and the Judicial Branch makes up almost 50% of the overall jobs in North America’s current market economy.
Democracy is a failed political system. The judicial branch was to remain the weakest in the Roman Democratic Theory to prevent a police state.
80% of our tax dollars and almost 50% of our economic industry?
Open your mind see the truth.
Crime needs to rise, drugs need to be of poor quality, why? More funding, more jobs, more power, more control.
The police forces have their own banks, who is the real problem?
Figure it out.
Organized crime is necessary to combat street level gangs and limit the property theft and violent crime.
Whereas police need the street level gangs and the petty crimes in order to keep expanding their corporation and its business of policing.
We’ve lost touch ladies and gentleman. Think of your children and their children, and their children’s children.
Wake up people… We have to deal with this and now.
First step: Pull the funding for the war on drugs and let it solve itself.
The groups whom succeed are meant to succeed.
Watch as the world grows from there…
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