Writing papers has been one of the oldest traditions in science. Indeed, digging up old journal articles written on paper made of swamp grass in long dead languages is still occurring. Though time, the evolution of writing papers has evolved to a rather complicated design so that we may root out nonsense experiments which draw foolish conclusions. I.E. peer review. There exists two fundamental necessities when writing papers.

One – perhaps the most important – is the ability to write an article according to accepted and standard methods. That subject has been adequately covered. Equally important rules follow:

  1. References. References should contain at least two review articles from big names in the field. You wouldn’t want to miss an opportunity to suck up to a potential reviewer. If you were to write an article on some synthesis of an epothilone, you may want to consider putting a reference in for Rich Taylor or KC Nicolaou. If you were to write a paper on protein folding, a good review by Ken Dill and Alan Fersht wouldn’t hurt your chances. And if you are doing something involving some new rotaxane – perhaps a nod to Stoddart and David Leigh is in order.
  2. Pretty pictures. A well laid out picture will never hurt your chances. When I read an article, I look for two things: charts and pictures. Placing a pretty picture at the top of the first page is an excellent way to get your reader (or reviewer) to immediately appreciate what you are trying to do. People fall in love with crystal structures.
  3. Breaking some of Whiteside’s rules. People who don’t speak English as a native language would certainly be better off if every paper were written with small words, in a similar style and as prosaically as possible. Honestly, that’s something to keep in mind, but Beethoven didn’t become famous because he followed all the rules, it’s because he broke them, if only on a few occasions, to set himself apart. We can’t all be Beethovens, a pleasing writing style isn’t something everyone is born with – but everyone certainly should have a unique style, since (at least in theory) everyone is a snowflake. Distinguishing yourself by referring to things as svelte, for instance (or being bold enough to give some process you just invented a cute name) is certainly a good idea. But we must always keep in mind that there is a fine line between cute and obnoxious and you don’t want to step over it.
  4. Easter Eggs. One of the most fun things about reading a good journal article is when you come across some little fact, even tangentially related to the paper, that makes you go ‘hmmm, cool.’ Tossing in such factoids is impressive and fun and even helps illustrate your point with something everyone can relate to. Such as the preceding post points out, the pKa of phenolic proton can indeed be higher than the proton of a para substituted benzoic acid. Not something you might want to spring on people at the significant other’s office party – but certainly something colleagues would appreciate.

I say all this because it helps ME read an article… So, it isn’t devoid of selfishness. Just keep in mind that reviewers and readers are people – typically very bright people – that are easily bored with research that is… you know… not going to change the world overnight and no one is interested in reading some boring article that will just blend in with all the other boring articles they read through the day.

UPDATE: Check out further suggestions if you’re interested in submitting to Nature.