» My E. coli brother's keeper
03/09/10 14:43 from The Curious Wavefunction
Would an anti-indole work? Antibiotic resistance is one of the best examples of evolution in real-time and it’s also one of the most serious medical problems of our time. Emerging resistance in bacteria like MRSA threatens to bring on a wa..

» Cursed Pine Nuts or Triglycerides?
03/09/10 13:19 from Just Chromatography
A few days ago I noticed that my taste was disturbed: no matter what I eat or drink I feel the bitter taste in my mouth. This bitter, metallic taste appears within seconds of chewing and it affects everything I eat even sweets! Initially I ..

» Forensic Application of Gas Chromatography
03/09/10 13:19 from Just Chromatography
These days gas chromatography (GC) is one of the primary analytical techniques used in every forensic laboratory. GC is widely used by forensic scientists - from analysis of body fluids for the presence of illegal substances, to testing of..

» Heat Flow through Hydrocarbon Chains
03/09/10 13:19 from Just Chromatography
Scientists have measured heat conduction through a monolayer of hydrocarbon chains using a novel technique. Researchers understand heat transfer on the scales of individual molecules and in solids, but there is still much to learn about the..

» Nano LC Sensitivity
03/09/10 13:19 from Just Chromatography
In theory, the analyte sensitivity increases on decreasing the column inner diameter; however, because of the very low sample volumes injected - 20-60 nL, nano liquid chromatography cannot be considered as an analytical method of high sensi..

» “Fast” HPLC better than UHPLC
03/09/10 13:19 from Just Chromatography
Research scientists from Schering-Plough Research Institute developed a rapid high-performance liquid chromatography (HPLC) technique that allows for efficient separation and analysis of pharmaceutical compounds. The method uses a short col..

» Fishy Chromatography
03/09/10 13:19 from Just Chromatography
Folks from India extracted 99.6% pure eicosapentaenoic acid (EPA) using silver ion (argentation) column chromatography from hydrolyzed sardine oil[1]. EPA and DHA (docosahexaenoic acid) are the two main long-chain polyunsaturated fatty aci..

» Columns for Gas Chromatography: Performance and Selection
03/09/10 13:19 from Just Chromatography
Choosing the right column is key in Gas Chromatography. "Columns for Gas Chromatography: Performance and Selection" is a new hands-on reference for scientists and technicians working with packed column and capillary column gas chromatograp..

» Motor Proteins in Nanotechnology
03/09/10 13:19 from Just Chromatography
The biological cell is basically a miniature factory, which contains a large collection of dedicated protein machines. In a Review, Martin van den Heuvel and Cees Dekker look at recent progress in using some of these proteins to move, mani..

» The Little Botanists
03/09/10 13:19 from Just Chromatography
I am continuing the series dedicated to the chromatography??s founder Mikhail Tsvet. So, in 1897 he moves to Russia from Switzerland, and here is his first impression of Russia: "...during the first six months that I have been in Russia, in..

» Unanswered Questions
03/09/10 13:19 from Just Chromatography
Today I studied my blog's statistics to see what keywords people use to search in Google and Yahoo! to get to the pages of my site. Here is what I found based on the last 60 days of statistics: People used 1966 various search terms The top ..

» Polymer Solar Cells Build for Two
03/09/10 13:19 from Just Chromatography
Researchers have developed a new method for producing tandem solar cells, in which two solar cells working together to use a wider range of the solar spectrum. The physical properties of the semiconductor materials in each cell allow one t..

» Asparagusic Acid, Anyone?
03/09/10 13:19 from Just Chromatography
Thank God for Greg's post "Odeur d'Asperge" over at Carbon Tet! The mystery is solved, and I thought my kidneys were failing and I would have to spend the rest of my life on dialysis. This spring I had become an avid admirer of the young as..

» Nanogenerators Powered By Heartbeat
03/09/10 13:19 from Just Chromatography
Scientists from Georgian Institute of Technology created a prototype nanogenerator that can generate electricity inside a human body. Tiny little devices traveling in our bloodstream while performing complete blood analysis and monitoring ..

» High Reactivity at Very Low Temperatures
03/09/10 13:19 from Just Chromatography
New research examines a class of reactions between neutral free radicals and neutral molecules that, unlike most reactions, happen rapidly at very low temperatures. Chemical reactions generally accelerate when temperature increase. However,..

» Cocaine Pollution
03/09/10 13:19 from Just Chromatography
Cocaine is presently the most abused substance in Americas; however, the stimulant is gaining new advocates at an alarming rate in western Europe as well. In 2005, a group of researches from Italy analyzed water samples from the Po River in..

» Columns in Nano LC
03/09/10 13:19 from Just Chromatography
As I mentioned in the last post from this series, capillary columns of 10–100 μm inner diameter are commonly used in nano-liquid chromatography setups. They are typically made either from fused silica or PEEK materials currently ..

» Carbon Nanoscrolls to Store Hydrogen
03/09/10 13:19 from Just Chromatography
As our planet is running out of petroleum resources, a new energy source must be found. Hydrogen is regarded as an ideal alternative to fossil fuel because of its abundance in environment, renewability, and zero emission. However, the most ..

» Translational vs Vibrational
03/09/10 13:19 from Just Chromatography
Has anyone seen today's issue of Science? There is a research paper by Shannon Yan and colleagues "Do Vibrational Excitations of CHD3 Preferentially Promote Reactivity Toward the Chlorine Atom?" I had a difficult time following the authors ..

» What is the response factor in chromatography?
03/09/10 13:19 from Just Chromatography
"What is the response factor in chromatography?" is a question on Yahoo Answers. So far there has been two answers: 1) A wordy and a bit confusing text book reply tailored more towards Gas Chromatography. Response Factor The size of a spect..

» HPLC for Pharmaceutical Scientists
03/09/10 13:19 from Just Chromatography
"HPLC for Pharmaceutical Scientists" is a new hardcover book edited by Yuri V. Kazakevich and Rosario LoBrutto with a price tag of $159 at Amazon. This is an excellent book for both novice and experienced pharmaceutical chemists that provi..

» Chinese Meds are Safe
03/09/10 13:19 from Just Chromatography
...well, the prescription ones at least. With Chinese manufacturers considering to increase exports of drug ingredients and perhaps even begin shipping finished drug products to the United States, an article "Trusting medicine from China: C..

» Definition of Nano Liquid Chromatography
03/09/10 13:19 from Just Chromatography
It is interesting to note that 20 years later there is still no clear definition of nano-LC. Due to a relatively large size of the columns used in nano-HPLC (10-140 μm), the method does not fall within the realm of the conventional definiti..

» Nano Liquid Chromatography - Reloaded
03/09/10 13:19 from Just Chromatography
Thanks to one of the readers of this blog - Farooq, I now have the full text of an excellent, 21-page review by the researches from Rome and Spain entitled "Recent applications in nanoliquid chromatography" (DOI 10.1002/jssc.200700061). Two..

» From Switzerland to Russia
03/09/10 13:19 from Just Chromatography
This is the next post from the series dedicated to 135th birthday anniversary of Prof. Tsvet, the chromatography's founder. Today, the application of the principle of a chromatographic substance separation is the foundation of many breakthr..

» Toxic Waste Eating Bacteria
03/09/10 13:19 from Just Chromatography
New research on sulfate-reducing bacteria may offer good news for bioremediation efforts to clean up acid mine drainages and other environments with high levels of harmful metals. Sulfate-reducing bacteria is known to extract metal dissolve..

» Plastic that grows in the field
03/09/10 13:19 from Just Chromatography
A chromium catalyst is the key to efficiently converting glucose to a chemical feedstock with potential to replace many uses of crude oil including pharmaceuticals, cosmetics and plastics, scientists from Pacific Northwest National Laborato..

» Organic Oxygen
03/09/10 13:19 from Just Chromatography
A simple, cheap treatment using just oxygen could allow organic produce growers to store their crops for longer and go a long way towards reducing the price of organic fruit and vegetables. I admit that I am into organic produce but mostly..

» Solandelactone E
03/09/10 12:37 from TotallySynthetic.com
Aggarwal, Robinson. ACIEE, 2010, EarlyView. DOI: 10.1002/anie.201003236 A question – how long does one spin-out natural products based on one particular method?  I ask this as this is the second synthesis I've written about this year..

» Manzamine A
03/09/10 12:37 from TotallySynthetic.com
Fukuyama, Toma, Kita. JACS, 2010, ASAP. DOI: 10.1021/ja103721s Ah – now this is a bit of a blast-from-the-past.  I knew I'd written something about this molecule before, so I had a quick rummage in the Tot. Syn. folder on my PC ̵..