Heath Leger died, some speculate from a drug OD. From here:

Six prescription drugs were found, including Ambien, Valium, anti-depressant Zoloft, Xanax, Zoplicone [sic] and Donormyl

So, this is The Chem Blog and not Variety and I don’t care too much about Leger’s death, but it’s curious that people jumped to drug overdose without asking anyone if it was really easy to OD on any of these drugs. The answer is that no, it’s painfully difficult to have a fatal OD on any of those drugs.There’s some inherent danger in Ambien, Zopiclone (both nonbenzodiazepine sleeping aids), Valium and Xanax, (both benzodiazepines), but you could down an entire bottle without dying.* Unless mixed with alcohol, they’re difficult to fatally OD on. As for the other two, I can’t say there are any known cases of a fatal ODs with Zoloft or Donormyl (aka Doxylamine aka Nyquil).

Of course, Ambien, Valium, Xanax and Zopiclone all act on the same receptors in the brain (them benzo receptors). Taking ALL of them may well fucking kill you. I don’t know. That’s a lot of fuckin’ with GABAA receptors.

*I say without dying but I refer only to, like, sudden death, which can actually happen, it’s just not easy to do or common. But they say you can drown in a thimble of water… who knows. I just know it’s really, really hard to kill yourself with these drugs alone… but that being said:

Let your good buddy Kyle educate you by sharing a “life moment”. In my rather limited experience, Ambien is horribly dangerous and should never, under any circumstances, be used by people who are unaccompanied by someone capable of restraining them. During undergrad, I had some an awful sunburn and was unable to sleep, so I got a script for Ambien (all legit, I’m sXe and all). The next morning I woke up, face down in my livingroom with my (very nice and expensive) cashmere overcoat lying in a melted pint of ice cream… I did not have a pint of ice cream in my house before I took the Ambien… I’ve never figured out where it came from. Fucked up shit. Bad juju. Avoid at all costs.

So, I’d say that it was not an OD. But if he was drinking a lot, all bets are off. Benzos can be quite dangerous in combination with other CNS depressants. But I mix shit in flasks and run them through finely powdered sand. What do I know?